MK-8719, a Novel and Selective O-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy
Deposition of hyperphosphorylated and aggregated tau protein in the central [...]
Deposition of hyperphosphorylated and aggregated tau protein in the central [...]
Regional glucose hypometabolism is a defining feature of Alzheimer disease [...]
Background: The abnormal hyperphosphorylation of the microtubule-associated protein tau plays a [...]
Neurofibrillary tangles (NFT), mainly consisting of fibrillar aggregates of hyperphosphorylated [...]