JNPL3 – Alectos Therapeutics

The emerging link between O-GlcNAc and Alzheimer disease

Regional glucose hypometabolism is a defining feature of Alzheimer disease [...]

Administrator2014-10-21T21:22:17-07:00October 21, 2014|Categories: Publications|Tags: 5XFAD, Alzheimer's, Amyloid, JNPL3, OGA, SFU, TAPP, Tau, Tau.P301L, Tg4510, Thiamet-G|

Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation

Oligomerization of tau is a key process contributing to the [...]

Administrator2012-02-26T00:28:51-08:00February 26, 2012|Categories: Publications|Tags: Alzheimer's, JNPL3, OGA, SFU, Tau, Thiamet-G|