{"id":213,"date":"2012-07-16T23:18:12","date_gmt":"2012-07-16T23:18:12","guid":{"rendered":"http:\/\/alectos.com\/content\/?p=213"},"modified":"2012-07-16T23:18:12","modified_gmt":"2012-07-16T23:18:12","slug":"alectos-nserc-pinto-sfu-cancer-metabolism","status":"publish","type":"post","link":"https:\/\/alectos.com\/alectos-content\/index.php\/2012\/07\/16\/alectos-nserc-pinto-sfu-cancer-metabolism\/","title":{"rendered":"Alectos Supports NSERC Funding for Prof. B.M. Pinto at SFU"},"content":{"rendered":"<p><strong>July 16, 2012<\/strong> \u2013 Alectos today announced its support for NSERC funding for the group of Prof. B.M. Pinto at Simon Fraser University, Department of Chemistry, in a project titled \u201cMolecular dynamics simulations of Ligand-Enzyme complexes for a novel target involved in cancer metabolism&#8221;.<\/p>\n<p>The collaboration between Alectos Therapeutics and the Pinto group at SFU aims to use high-level computer algorithms to model and predict the binding mode of small-molecule inhibitors targeting an enzyme involved in tumour metabolism. This project will capitalize on the unique molecular modeling capabilities of the Pinto group at SFU to characterize the three-dimensional structure and energetics of inhibitor binding to more fully understand protein-inhibitor interactions on a molecular level. Using a collaborative approach, Alectos and the Pinto group will carry out computational modeling studies on a variety of enzyme inhibitors. The success of this project may lead to a better understanding of inhibitor binding, cellular metabolism, and ultimately a new treatment for cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>July 16, 2012 \u2013 Alectos today announced its support for  [&#8230;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[30],"tags":[27,31,32,20],"class_list":["post-213","post","type-post","status-publish","format-standard","hentry","category-news","tag-cancer-metabolism","tag-nserc","tag-pinto","tag-sfu"],"_links":{"self":[{"href":"https:\/\/alectos.com\/alectos-content\/index.php\/wp-json\/wp\/v2\/posts\/213","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/alectos.com\/alectos-content\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/alectos.com\/alectos-content\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/alectos.com\/alectos-content\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/alectos.com\/alectos-content\/index.php\/wp-json\/wp\/v2\/comments?post=213"}],"version-history":[{"count":0,"href":"https:\/\/alectos.com\/alectos-content\/index.php\/wp-json\/wp\/v2\/posts\/213\/revisions"}],"wp:attachment":[{"href":"https:\/\/alectos.com\/alectos-content\/index.php\/wp-json\/wp\/v2\/media?parent=213"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/alectos.com\/alectos-content\/index.php\/wp-json\/wp\/v2\/categories?post=213"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/alectos.com\/alectos-content\/index.php\/wp-json\/wp\/v2\/tags?post=213"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}